Author

Nicholas C. Jacobs

Washington University in St. LouisORCID 0000-0002-2617-6173Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Jiwoong ParkiD· 2 shared Timothy R. PetersoniD· 2 shared Anastasiia OnyshchenkoiD· 1 shared Ariella L. G. Coler-ReillyiD· 1 shared Damon T. BurrowiD· 1 shared India C. Bradley· 1 shared Jan E. CaretteiD· 1 shared Jinmei LiiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersSystems Biology

Jiwoong ParkORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintApr 5, 2023

Cell fitness is an omniphenotype

Nicholas C. Jacobs, Jiwoong Park, Nancy L. Saccone, Timothy R. Peterson

The paper proposes using cell fitness as a universal phenotype to prioritize gene and drug targets in disease research, showing its broad applicability across diseases and cost-effectiveness.

2 citations

humanstatistical model

𝕏 PostBluesky

GenomicsbioRxivPreprintApr 10, 2020

Sphingolipid Biosynthesis Inhibition As A Host Strategy Against Diverse Pathogens

Sandeep Kumar, Jinmei Li, Jiwoong Park…·Timothy R. Peterson

This study identifies that multiple cationic amphipathic drugs (CADs) share molecular similarities with chloroquine and inhibit sphingolipid biosynthesis, suggesting their potential as antiviral agents against diverse pathogens including SARS-CoV-2.

3 citations

humanstatistical model

𝕏 PostBluesky