Tim Chico

The paper compares segmentation methods for zebrafish brain vasculature, finds U-Net outperforms SegNet, and highlights the effectiveness of Sato enhancement and Otsu thresholding.

This paper presents a 3D image analysis pipeline for quantifying zebrafish brain vasculature, showing it is robust and provides novel insights into vascular biology.

This study quantifies how absent blood flow affects vascular development in zebrafish cerebral and trunk vasculature, finding more severe effects in the brain.

This study shows that inhibiting TOR and ERK pathways in endoglin mutant zebrafish reduces vascular abnormalities associated with HHT.

The paper identifies asymmetric Hapln1a expression in zebrafish heart development, showing it drives ECM expansion and promotes asymmetric heart morphogenesis through interaction with laterality cues.

This study shows glucose exposure harms the neurovascular unit and behavior in zebrafish, but sodium nitroprusside reverses these effects.

The paper describes the discovery of transient NO-containing spherical structures in zebrafish cerebral endothelial cells during development, showing their dependence on Notch signaling.

The paper investigates the roles of foxc1a and foxc1b in regulating angiogenesis from arteries and veins in zebrafish by modulating VEGF and Dll4/Notch signaling.