Author
Novo Nordisk FoundationORCID 0000-0002-2738-0811Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Frances Rocamora, Chen‐Lin Hsieh, Sanne Schoffelen…·Nathan E. Lewis
This study generates glycoengineered recombinant alpha1-antitrypsin with in vitro and in vivo activities comparable to plasma-derived A1AT, offering a sustainable therapeutic alternative.
Haining Li, Angelo Gabriel Peralta, Sanne Schoffelen…·Nathan E. Lewis
LeGenD predicts N-glycan structures and their abundance using lectin-binding patterns and AI, trained on glycoprofiles from recombinant proteins.
Haining Li, Austin W.T. Chiang, Vahid Gazestani…·Nathan E. Lewis
The paper investigates the phenotypic and transcriptional effects of glycoengineering in CHO cells, identifying distinct clusters and molecular mechanisms associated with different glycosyltransferase modifications.
Hooman Hefzi, Iván Martínez‐Monge, Igor Marín de Mas…·Nathan E. Lewis
This study eliminates the Warburg Effect in mammalian cells by knocking out lactate dehydrogenase and feedback regulators, maintaining growth rate while reducing lactate production.
Dongdong Lin, Hima Bindu Yalamanchili, Xinmin Zhang…·Baohong Zhang
CHOmics is a web-based tool for analyzing and visualizing multi-omics data from CHO cell lines, offering integrated analysis, customization, and visualization features.