Sara Petersen Bjørn

This study generates glycoengineered recombinant alpha1-antitrypsin with in vitro and in vivo activities comparable to plasma-derived A1AT, offering a sustainable therapeutic alternative.

The paper investigates the phenotypic and transcriptional effects of glycoengineering in CHO cells, identifying distinct clusters and molecular mechanisms associated with different glycosyltransferase modifications.

This study eliminates the Warburg Effect in mammalian cells by knocking out lactate dehydrogenase and feedback regulators, maintaining growth rate while reducing lactate production.

CHOmics is a web-based tool for analyzing and visualizing multi-omics data from CHO cell lines, offering integrated analysis, customization, and visualization features.

The paper identifies protein-protein interactions supporting recombinant protein secretion using BioID and Bayesian modeling, finding key roles for oxidative folding enzymes in disulfide bond formation.

This paper describes a method to evolve and functionalize biosensors in yeast by optimizing ligand specificity and transfer functions through directed evolution.