Author

Lenka Dohnalová

University of PennsylvaniaORCID 0000-0002-2761-2547Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Christoph A. ThaissiD· 2 shared A. Sloan DevliniD· 1 shared Alana M. McSweeniD· 1 shared Cecilia H. KimiD· 1 shared Chelsea E. PowelliD· 1 shared Daniela Min Jing Che Jin· 1 shared Emma Elizabeth FurthiD· 1 shared Emma Loeffler· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Christoph A. ThaissORCID

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2 papers

Recent·Most cited

Cell BiologyProceedings of the National Academy of SciencesPeer-reviewedMar 11, 2026

Gut Microbiome-Produced Bile Acid Metabolite Lengthens Circadian Period in Host Intestinal Cells

Chelsea E. Powell, Alana M. McSween, Lenka Dohnalová…·A. Sloan Devlin

The paper identifies lithocholic acid as a bile acid metabolite that modulates circadian rhythms in intestinal cells by affecting core clock proteins and feedback loops.

7 citationstop 1%

humanmouse

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Cell BiologybioRxivPreprintFeb 10, 2025

Dietary manipulation of intestinal microbes prolongs survival in a mouse model of Hirschsprung disease

Naomi E. Butler Tjaden, Megan J. Liou, Sophie E. Sax…·Robert O. Heuckeroth

This study shows that diet can significantly affect survival in a mouse model of Hirschsprung disease by altering gut microbes, metabolites, and epithelial gene expression.

2 citations

mousebulk RNA-seq

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