Author

Naomi E. Butler Tjaden

Children's Hospital of PhiladelphiaORCID 0000-0002-9507-4103Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Christoph A. ThaissiD· 1 shared Christopher W. Seidel· 1 shared Daniela Min Jing Che Jin· 1 shared Emma Elizabeth FurthiD· 1 shared Emma Loeffler· 1 shared Guang Yan· 1 shared Jessica Raab· 1 shared Joshua D. EisenbergiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

Christoph A. ThaissORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Dietary manipulation of intestinal microbes prolongs survival in a mouse model of Hirschsprung disease

Naomi E. Butler Tjaden, Megan J. Liou, Sophie E. Sax, Nejia Lassoued, Meng Lou, Sabine Schneider, Katherine Beigel, Joshua D. Eisenberg, Emma Loeffler, Sierra E. Anderson, Guang Yan, Lev Litichevskiy, Lenka Dohnalová, Yixuan Zhu, Daniela Min Jing Che Jin, , Robert O. Heuckeroth

This study shows that diet can significantly affect survival in a mouse model of Hirschsprung disease by altering gut microbes, metabolites, and epithelial gene expression.

bioRxiv · Feb 10, 2025 · PreprintCell Biology

Rdh10-mediated Retinoic Acid Signaling Regulates the Neural Crest Cell Microenvironment During ENS Formation

Naomi E. Butler Tjaden, Stephen R. Shannon, Christopher W. Seidel, Melissa Childers, Kazushi Aoto, Lisa L. Sandell, Paul A. Trainor

This study identifies Rdh10 as a key regulator of retinoic acid signaling that controls neural crest cell migration during enteric nervous system formation, leading to intestinal aganglionosis in its absence.

bioRxiv · Jan 23, 2025 · PreprintDevelopmental Biology