Irene de Lázaro

This study shows that loss of PKP2 in cardiomyocytes induces pro-inflammatory senescence in non-myocytes and premature cardiac aging, linking desmosomal arrhythmogenic cardiomyopathy to cellular senescence and aging mechanisms.

This study shows that cyclic OKSM expression rejuvenates adult cardiomyocytes in mice with heart failure, improving systolic function without dedifferentiation.

This study evaluates the impact of graphene oxide exposure on reference gene expression in human and mouse cells, showing significant dysregulation in ribosomal proteins and common calibrators.

This study induces transient cell reprogramming in mouse skeletal muscle using plasmid DNA to enhance tissue regeneration after injury.