Author
University of CambridgeORCID 0000-0002-2791-6727Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Adam Harmanec, Alexander D Dagg, Jan Kamenický…·Zuzana Kadlecová
Shape2Fate tracks and classifies exocytic and endocytic carriers in live cells using morphology-aware deep learning, revealing pathway-specific exo-endocytic coordination rules.
Sophia Y. Breusegem, Jack W. Houghton, Raquel Romero-Bueno…·Delphine Larrieu
A whole genome multiparametric CRISPR screen in progeria identifies new pathways that can reverse cellular aging phenotypes by targeting protein translation and related processes.
Alex S. Nicholson, David A. Priestman, Robin Antrobus…·Janet Elwyn Deane
This study develops i3Neuron models of Tay-Sachs and Sandhoff diseases, revealing plasma membrane remodeling and synaptic dysfunction due to GM2 ganglioside accumulation.
Elena Pavlova, Dorit Lev, Marina Michelson…·Timothy Martin Cox
The paper identifies a missense mutation in VPS33A causing an attenuated juvenile form of mucopolysaccharidosis plus and shows potential therapeutic interventions.