Author

Emilia Komulainen

University of SussexORCID 0000-0002-2804-1678Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Organism:Drosophila· 1 Assay:imaging· 1 Organism:zebrafish· 1

Frequent Co-Authors

Kevin StarasiD· 2 shared Filip K. JaniakiD· 1 shared Jack BadmaniD· 1 shared Kate FennelliD· 1 shared Keith W. CaldecottiD· 1 shared Limei Ju· 1 shared Lucia L. Prieto-GodinoiD· 1 shared Michael Ross BaleiD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Kevin StarasORCID

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2 papers

Recent·Most cited

Aberrant PARP1 Activity Couples DNA Breaks to Deregulated Presynaptic Calcium Signalling and Lethal Seizures

Emilia Komulainen, Jack Badman, Stephanie A. Rey, Stuart L. Rulten, Limei Ju, Kate Fennell, Peter J. McKinnon, Kevin Staras, Keith W. Caldecott

This study shows that aberrant PARP1 activity at unrepaired DNA breaks causes deregulated presynaptic calcium signaling and lethal seizures in Xrcc1-defective mice, suggesting PARP inhibition as a therapeutic strategy.

bioRxiv · May 15, 2020 · PreprintNeuroscience

Divergent excitation two photon microscopy for 3D random access mesoscale imaging at single cell resolution

Filip K. Janiak, Philipp Bartel, Michael Ross Bale, Takeshi Yoshimatsu, Emilia Komulainen, Mingyi Zhou, Kevin Staras, Lucia L. Prieto-Godino, Thomas Euler, Miguel Maravall, Tom Baden

This paper introduces a new two-photon microscopy technique that expands the 3D field of view while maintaining single-cell resolution, enabling more comprehensive neuronal activity imaging in multiple organisms.

bioRxiv · Oct 29, 2019 · PreprintNeuroscience