Tania Roskams

This study shows 4'-fluorouridine inhibits Oropouche virus replication in vitro and in animal models, with no resistant variants observed.

The paper identifies purine metabolism as a common altered pathway in ADPKD cysts and cell models, showing its modulation suppresses cyst formation in vitro.

The paper reconstructs gene regulatory networks in human adult pancreatic cell types and identifies key transcription factors regulating cell identity.