Author

Zeguo Zhao

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-2901-5033Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Anthony F. DaniyaniD· 1 shared Caleb A. LareauiD· 1 shared Christopher Austin KlebanoffiD· 1 shared Christopher S. HackettiD· 1 shared Doron BeteliD· 1 shared Erica J. BrophyiD· 1 shared Fei YiiD· 1 shared Friederike DündariD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Anthony F. DaniyanORCID

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1 paper

Recent·Most cited

CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit

Fei Yi, Tal Cohen, Natalie Zimmerman, Friederike Dündar, Paul Zumbo, Razan Eltilib, Erica J. Brophy, Hannah Arkin, Judith Feucht, Michael V. Gormally, Christopher S. Hackett, Korbinian Nepomuk Kropp, Iñaki Etxeberría, Smita S. Chandran, Zeguo Zhao, , Christopher Austin Klebanoff

This study identifies FASLG expression patterns and shows that FAS-L/FAS auto-regulation governs CAR-T and CAR-NK cell persistence, enhancing antitumor efficacy when FAS is inhibited.

Nature Cancer · Jul 22, 2025Peer-reviewedImmunology