Soraya I. Shehata

Transcriptomic cytoarchitecture reveals principles of human neocortex organization

The paper uses single nucleus RNA-sequencing to analyze human cortical areas, revealing cell type proportions and gene expression patterns that correlate with functional connectivity and areal specialization.

Single-cell RNA-seq uncovers shared and distinct axes of variation in dorsal LGN neurons in mice, non-human primates and humans

The paper uses single-cell RNA-seq to analyze relay neurons in the dLGN across species, finding subtle transcriptomic differences compared to morphological and functional distinctions.

Genome-wide binding analysis of 195 DNA Binding Proteins reveals "reservoir" promoters and human specific SVA-repeat family regulation

The paper re-analyzes ENCODE data to identify reservoir promoters and human-specific SVA-repeat regulation using reproducible methods.

Transcriptomic evidence that von Economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons

The paper identifies von Economo neurons as a regionally specialized subtype of extratelencephalic-projecting excitatory neurons using single nucleus RNA-sequencing and cross-species comparisons.

Conserved cell types with divergent features between human and mouse cortex

The paper compares cell types in human and mouse cortex using single nucleus RNA-sequencing, finding conserved architecture with species-specific differences.

Equivalent high-resolution identification of neuronal cell types with single-nucleus and single-cell RNA-sequencing

The paper shows that single-nucleus and single-cell RNA-seq can equally identify neuronal cell types in mouse visual cortex when intronic sequences are included.

Transcriptomic and morphophysiological evidence for a specialized human cortical GABAergic cell type

The paper identifies a novel human cortical GABAergic interneuron subtype with unique transcriptomic, morphological, and physiological features not observed in rodents.