Macarena Morillo‐Huesca

Asparagine endopeptidase promotes radioresistance in breast cancer through ATR pathway modulation

This study identifies AEP's role in promoting radioresistance in breast cancer by modulating the ATR pathway and PPP1R10 levels, showing AEP-high/ATR-low as a biomarker for radioresistant patients.

FGFR1 inhibition prevents metabolic adaptation associated with therapy resistance in glioblastoma

This study identifies FGFR1 as a key driver of TMZ resistance in GBM through metabolic rewiring and cell cycle regulation, showing that FGFR1 inhibition restores TMZ sensitivity in preclinical models.

Functional impact of the H2A.Z histone variant during meiosis in Saccharomyces cerevisiae

This study investigates the role of H2A.Z histone variant in meiosis of Saccharomyces cerevisiae, showing its impact on meiotic progression, sporulation, and checkpoint responses.