Sine Mandrup Bertozzi

This study shows that a transient developmental excitation-inhibition imbalance causes lasting social brain circuit dysfunction in mice, with behavioral and transcriptional consequences.

This study identifies CDC42 inhibitors that reduce vessel branching in both normal skin and tumors, offering potential for treating skin cancer and angiogenesis-related diseases.

This paper investigates brain network and behavioral changes in a mouse model of CTD and shows that perinatal gene therapy can partially reverse some symptoms but not all.

This paper designs a CDC42 effector interaction inhibitor (ARN22089) that shows anti-cancer activity by blocking tumor invasion and angiogenesis.

This study uses chemogenetic-fMRI to identify brain regions activated by serotonergic stimulation, showing region-specific effects rather than global activity changes.