Author

Atiyeh Sadat Sharifzadeh

University of MilanORCID 0000-0002-2922-8944Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Albano C. MéliiD· 1 shared Alessandro PorroiD· 1 shared Ana Maria GomeziD· 1 shared Andrea SaponaroiD· 1 shared Anna MoroniiD· 1 shared Dario DiFrancescoiD· 1 shared Gerhard ThieliD· 1 shared Hugo Benoit· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Albano C. MéliORCID

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1 paper

Recent·Most cited

Animal-free recombinant nanobody rescues HCN4 channel deficit in sinus node dysfunction

Atiyeh Sadat Sharifzadeh, Roberta Castelli, Alessandro Porro, Pietro Mesirca, Romain Perrier, Ana Maria Gomez, Hugo Benoit, Albano C. Méli, Luca Maria Giovanni Palloni, Dario DiFrancesco, Matteo Elia Mangoni, Gerhard Thiel, Andrea Saponaro, Anna Moroni

This study identifies a recombinant nanobody that specifically activates HCN4 channels and rescues sinus node dysfunction in a patient with a loss-of-function mutation.

bioRxiv · Mar 20, 2025 · PreprintBiophysics