Mary‐Elizabeth Patti

This study shows that folic acid polyglutamylation activates MAP2K5 signaling to promote adipocyte lipid breakdown, revealing a novel role for folate in lipid homeostasis.

The paper identifies distinct adipocyte subsets in human white adipose tissue with different metabolic profiles and links TSHZ3 to their regulation and metabolic disease associations.

The paper shows that inhibiting bromodomain proteins like BRD4 reduces FGF15/19 expression, leading to hyperglycemia, and that overexpressing FGF19 can reverse these effects.

The paper identifies mediators of improved glycemia after gastric bypass surgery using a high-throughput mediation analysis method applied to plasma proteome and metabolome data.