Author

Eric Frapy

Centre National de la Recherche ScientifiqueORCID 0000-0002-2958-6960Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Caroline ReisacheriD· 2 shared Laurence ArbibeiD· 2 shared Abdelali JaliliD· 1 shared Ahmed HamaïiD· 1 shared Christophe DesterkeiD· 1 shared Clémence DurueliD· 1 shared David SkurnikiD· 1 shared Eliane PiaggioiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

Caroline ReisacherORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

CBX3 Deletion Overcomes Ferroptosis Resistance in Colorectal Cancer by Targeting IFNγ/SLC7A11/SLC3A2 Axis

Yao Xiang, Yuanji Fu, Christophe Desterke, Éric Batsché, Abdelali Jalil, Rima Elhage, Clémence Duruel, Jean-Christophe Beche, Eric Frapy, David Skurnik, Caroline Reisacher, Sedlik Christine, Eliane Piaggio, Laurence Arbibe, Ahmed Hamaï, Yunhua Chang

This study shows that CBX3 deletion increases ROS and lipid ROS levels in CRC cells, sensitizing them to ferroptosis by disrupting the IFNγ/SLC7A11/SLC3A2 axis.

bioRxiv · Oct 27, 2026 · PreprintCancer Biology

The VapBC Toxin Antitoxin System Enhances Shigella flexneri Fitness Through Coordination of Metabolic Stress Adaptation and Virulence

Estelle Saifi, Elisabeth Ageron, Keith T. Egger, Caroline Reisacher, Eric Frapy, Morgan Lambérioux, Shelley M. Payne, Jost Enninga, Laurence Arbibe

This study shows the VapBC toxin-antitoxin system in Shigella flexneri enhances bacterial fitness by coordinating metabolic stress adaptation, virulence, and immune evasion during infection.

bioRxiv · Jun 29, 2025 · PreprintMicrobiology