Author

Keith T. Egger

Institut PasteurORCID 0000-0003-2119-3334Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:electronic health records· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metagenomics· 1

Frequent Co-Authors

Jost EnningaiD· 2 shared Anastasia D. GaziiD· 1 shared Anna Sartori-RuppiD· 1 shared Camila ValenzuelaiD· 1 shared Cammie F. LesseriD· 1 shared Caroline ReisacheriD· 1 shared Elif Begüm GökerküçükiD· 1 shared Elisabeth AgeroniD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Jost EnningaORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 21, 2025

Virus-like particle capture reveals coordination of actin remodeling during Shigella flexneri entry by host proteins

María Luisa Gil-Marqués, Matthew S. Fish, Le Anh Thu Pham…·Poyin Chen

The paper identifies 14-3-3ζ and CAP2 as host proteins required for actin remodeling during Shigella flexneri entry, showing their coordinated role in membrane ruffle formation.

DOI 10.1101/2025.10.21.683715

humanproteomics

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MicrobiologybioRxivPreprintJun 29, 2025

The VapBC Toxin Antitoxin System Enhances Shigella flexneri Fitness Through Coordination of Metabolic Stress Adaptation and Virulence

Estelle Saifi, Elisabeth Ageron, Keith T. Egger…·Laurence Arbibe

This study shows the VapBC toxin-antitoxin system in Shigella flexneri enhances bacterial fitness by coordinating metabolic stress adaptation, virulence, and immune evasion during infection.

DOI 10.1101/2025.06.29.662172

bacteria (other)metagenomics

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MicrobiologyPLoS BiologyPeer-reviewedMay 1, 2025

TYPE THREE SECRETION SYSTEM-INDUCED MECHANOPORATION OF VACUOLAR MEMBRANES

Léa Swistak, Marvin Albert, Camila Valenzuela…·Jost Enninga

This study identifies mechanoporation via the Type Three Secretion System as a mechanism by which Shigella flexneri breaches vacuolar membranes to access the cytosol.

7 citations

humanelectronic health records

𝕏 PostBluesky