Author

Marlene Thorsen Mørch

University of CalgaryORCID 0000-0002-2991-6472Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Rui LiiD· 2 shared Voon Wee YongiD· 2 shared Alexandre PratiD· 1 shared Antonio Mendes· 1 shared Brian Mark LozinskiiD· 1 shared Carlos Rodrigo Camara-LemarroyiD· 1 shared Cenxiao Li· 1 shared Chang‐Chun LingiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Rui LiORCID

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2 papers

Recent·Most cited

Pathogenic T-bet+ memory B cells worsen multiple sclerosis through myeloid cell activation

Rajiv W. Jain, Maria Goiko, Antonio Mendes, Sara Xue, Salma Zein, Rianne Petra Gorter, Marlene Thorsen Mørch, Alexandre Prat, Rui Li, Voon Wee Yong

This study identifies T-bet+ memory B cells as pathogenic in MS by activating microglia/macrophages via IFN-γ, worsening EAE and demyelination.

bioRxiv · Sep 5, 2026 · PreprintImmunology

Aging-enhanced accumulation of fibroblasts excludes oligodendrocytes in demyelinated lesions

Brian Mark Lozinski, George S. Melchor, Charlotte D’Mello, Rianne P. Gorter, Yifei Dong, Samira Ghorbani, Cenxiao Li, Marlene Thorsen Mørch, Dorsa Moezzi, Rajiv Jain, Parisa Etemadi Nezhad, Chang‐Chun Ling, Carlos Rodrigo Camara-Lemarroy, Rui Li, Jeffrey K. Huang, Voon Wee Yong

This study shows that fibroblasts accumulate in demyelinated spinal cord lesions in mice, excluding oligodendrocyte precursor cells, and this effect is more pronounced with age.

Journal of Neuroinflammation · Jul 25, 2026Peer-reviewedNeuroscience