Author

Rui Li

Fujian Medical UniversityORCID 0000-0002-7210-8358Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Rui Li17 papers · University of Massachusetts Chan Medical School

Biology Disciplines

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Immunology· 3 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 3 Organism:human· 3 Organism:mouse· 2 Assay:flow cytometry· 1

Frequent Co-Authors

Amit Bar‐OriD· 2 shared Ayman RezkiD· 2 shared Gautier BrévilleiD· 2 shared Marlene Thorsen MørchiD· 2 shared Voon Wee YongiD· 2 shared Alexandre PratiD· 1 shared Amaar MarefiiD· 1 shared Amy Tara WaldmaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

Amit Bar‐OrORCID

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Author profile →

4 papers

Recent·Most cited

Pathogenic T-bet+ memory B cells worsen multiple sclerosis through myeloid cell activation

Rajiv W. Jain, Maria Goiko, Antonio Mendes, Sara Xue, Salma Zein, Rianne Petra Gorter, Marlene Thorsen Mørch, Alexandre Prat, Rui Li, Voon Wee Yong

This study identifies T-bet+ memory B cells as pathogenic in MS by activating microglia/macrophages via IFN-γ, worsening EAE and demyelination.

bioRxiv · Sep 5, 2026 · PreprintImmunology

Aging-enhanced accumulation of fibroblasts excludes oligodendrocytes in demyelinated lesions

Brian Mark Lozinski, George S. Melchor, Charlotte D’Mello, Rianne P. Gorter, Yifei Dong, Samira Ghorbani, Cenxiao Li, Marlene Thorsen Mørch, Dorsa Moezzi, Rajiv Jain, Parisa Etemadi Nezhad, Chang‐Chun Ling, Carlos Rodrigo Camara-Lemarroy, Rui Li, Jeffrey K. Huang, Voon Wee Yong

This study shows that fibroblasts accumulate in demyelinated spinal cord lesions in mice, excluding oligodendrocyte precursor cells, and this effect is more pronounced with age.

Journal of Neuroinflammation · Jul 25, 2026Peer-reviewedNeuroscience

Abnormal pro-inflammatory immune cell responses precede clinical onset of hypertensive disorders of pregnancy

Ayman Rezk, Chelsea A. DeBolt, Gautier Bréville, Rui Li, Valerie A Riis, Liqhwa Ncube, Fatoumata Barry, Michal A. Elovitz, Amit Bar‐Or

The paper identifies a pro-inflammatory immune cell signature in pregnant women before the onset of hypertensive disorders of pregnancy.

bioRxiv · Aug 4, 2025 · PreprintImmunology

Pediatric cerebrospinal fluid immune profiling distinguishes pediatric-onset multiple sclerosis from other pediatric-onset acute neurological disorders

Diego A. Espinoza, Tobias Zrzavy, Gautier Bréville, Simon Thebault, Amaar Marefi, Ina Mexhitaj, Luana D. Yamashita, Mengyuan Kan, Micky Bacchus, Jessica Legaspi, Samantha Fernandez, Anna Melamed, Mallory Stubblebine, Yeseul Kim, Zachary Martinez, , Amit Bar‐Or

This study identifies immune profiles in pediatric cerebrospinal fluid to differentiate pediatric-onset multiple sclerosis from other inflammatory neurological disorders.

bioRxiv · Feb 27, 2025 · PreprintImmunology