Mara Lawniczak

Souporcell clusters single-cell RNAseq data using genetic variants to accurately assign genotypes, detect doublets, and estimate ambient RNA without reference genotypes.

The paper creates a comprehensive single-cell transcriptome atlas of the Plasmodium berghei life cycle and applies it to define stages in human malaria parasites.

This paper presents a high-quality de novo genome assembly of a single Anopheles coluzzii mosquito using a modified PacBio protocol, achieving high contiguity and completeness with low DNA input.

This study applies single-cell RNA-sequencing to malaria parasites, revealing transcriptional variation and novel gene expression patterns in sexual stages.

The paper sequences genomes of 765 malaria vector mosquitoes to study genetic diversity and insecticide resistance.

The paper investigates the evolutionary dynamics of sex-biased genes in four Anopheles mosquito species, finding female-biased genes evolve faster than male-biased ones due to sex-specific challenges.

The paper demonstrates that Y chromosomes from two malaria vector species in the Anopheles gambiae complex function interchangeably, suggesting no hybrid incompatibility loci on the Y and enabling potential cross-species sex-distorting Y drive interventions.