Arthur M. Talman

The paper generates high-quality chromosome-level genomes for three Plasmodium species from natural infections, improving understanding of their biology and evolution.

The paper develops molecular markers to distinguish male and female gametocytes in Plasmodium relictum using single-cell RNA sequencing, outperforming microscopy in sensitivity and detection.

This study examines the health impacts of asymptomatic malaria in semi-wild chimpanzees, finding systemic immune changes and physiological stress indicators.

This study shows GBP1 is recruited to actin-rich pedestals formed by extracellular pathogens, promoting pyroptosis and IL-18 release, independent of LPS.

This study identifies two spore types in the marine parasite Amoebophrya, revealing sexual and infectious functions, with smaller spores infecting hosts and larger spores undergoing meiosis.

This study presents a single-cell transcriptome atlas of Plasmodium falciparum sexual development, revealing transcriptional heterogeneity in naturally infected individuals.

The paper identifies ten genes critical for male and female sexual development in Plasmodium berghei and reveals a regulatory cascade governing gametogenesis.

Souporcell clusters single-cell RNAseq data using genetic variants to accurately assign genotypes, detect doublets, and estimate ambient RNA without reference genotypes.

The paper creates a comprehensive single-cell transcriptome atlas of the Plasmodium berghei life cycle and applies it to define stages in human malaria parasites.

This study applies single-cell RNA-sequencing to malaria parasites, revealing transcriptional variation and novel gene expression patterns in sexual stages.