Virginia M. Howick

This study uses single-cell RNA sequencing to show that T. cruzi trypomastigote cells express trans-sialidase-like superfamily genes with high heterogeneity and no recurrent combinations.

The paper shows that regional genetic variation in Plasmodium falciparum affects transmissibility to different mosquito species by altering midgut adhesion interactions.

This study maps the single-cell transcriptional and metabolic changes in Aedes aegypti midgut and fat body after a bloodmeal, revealing diverse cell populations and a novel fat body-yolk cell type.

This study creates a single-cell atlas of Culex tarsalis midgut cells during West Nile virus infection, revealing cell-type-specific differences in viral replication and immune responses.

The paper uses single-cell RNA sequencing to identify and characterize sexual stages in Trypanosoma brucei, revealing gene expression patterns associated with gamete formation.

The paper uses single-cell transcriptomics to map gene usage and developmental trajectories of Plasmodium falciparum during mosquito transmission.

The paper creates a comprehensive single-cell transcriptome atlas of the Plasmodium berghei life cycle and applies it to define stages in human malaria parasites.