Author

Karel Aceituno

University of Southern CaliforniaORCID 0000-0002-3021-5104Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Allison BirnbaumiD· 2 shared Constanza J. CortésiD· 2 shared Jocelyne LeoniD· 2 shared José A. Godoy-LugoiD· 2 shared Cristal M. HilliD· 1 shared Emily Morales· 1 shared Hash Brown TahaiD· 1 shared Ian MatthewsiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Allison BirnbaumORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 24, 2026

Long-term voluntary exercise reveals limited translation of hippocampal molecular responses into neuroprotection in 5xFAD mice

Karel Aceituno, Katrina Granger, Jocelyne Leon…·Constanza J. Cortés

This study shows that long-term voluntary exercise in 5xFAD mice leads to limited molecular changes in the hippocampus that do not translate into significant neuroprotection.

DOI 10.64898/2026.09.16.752181

mousebulk RNA-seq

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NeuroscienceGeroSciencePeer-reviewedSep 13, 2024

Activation of the muscle-to-brain axis ameliorates neurocognitive deficits in an Alzheimer disease mouse model via enhancing neurotrophic and synaptic signaling

Hash Brown Taha, Allison Birnbaum, Ian Matthews…·Constanza J. Cortés

This study shows that enhancing the muscle-to-brain axis in Alzheimer's disease mice reduces amyloid plaques and improves cognitive function through neurotrophic and synaptic signaling.

15 citationstop 5%

mouseexperimental assay

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