Author

Cristal M. Hill

University of Southern CaliforniaORCID 0000-0002-0722-9049Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

Khristina E. Young· 3 shared José A. Godoy-LugoiD· 2 shared Aeowynn J. CoakleyiD· 1 shared Ahvital Artison· 1 shared Allison BirnbaumiD· 1 shared Amy ChristenseniD· 1 shared Athena AlcalaiD· 1 shared Bérénice Anath BenayouniD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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3 shared papersNeuroscience

Khristina E. Young

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Long-term voluntary exercise reveals limited translation of hippocampal molecular responses into neuroprotection in 5xFAD mice

Karel Aceituno, Katrina Granger, Jocelyne Leon, José A. Godoy-Lugo, Khristina E. Young, Tiarra Joseph, Kailin Liu, Iris Daphne Kruijff, Emily Morales, Mia Hakian, Allison Birnbaum, Rik van der Kant, Cristal M. Hill, Constanza J. Cortés

This study shows that long-term voluntary exercise in 5xFAD mice leads to limited molecular changes in the hippocampus that do not translate into significant neuroprotection.

bioRxiv · Sep 24, 2026 · PreprintNeuroscience

Form and function of actin impacts actin health and aging.

Maxim Averbukh, Hunter T. Nelson, Tiffany V. Wang, Caitlin M. Lange, Athena Alcala, Juri Kim, Daniella Suh, Matthew Vega, Shihong Max Gao, Naibedya Dutta, Khristina E. Young, Rebecca Aviles Barahona, Aeowynn J. Coakley, Joe A. Gerke, Sofia F. Odron, , Ryo Higuchi‐Sanabria

This study investigates how actin structure and function affect aging in C. elegans and finds that actin dysfunction accelerates aging hallmarks and correlates with human age-related decline in gait speed.

iScience · Aug 24, 2026Peer-reviewedCell Biology

Females Adapt to Dietary Protein Restriction on Enhanced Gut-Brain Axis during Aging

Prerana Vaddi, José A. Godoy-Lugo, Khristina E. Young, Yvann Batamack, Michael Donkor, Ahvital Artison, Amy Christensen, Christian J. Pike, Cristal M. Hill

This study shows that dietary protein restriction improves metabolic and cognitive health in aged female mice by altering the gut microbiome.

bioRxiv · Jul 3, 2026 · PreprintPhysiology