Author

Karl Ekwall

Karolinska InstitutetORCID 0000-0002-3029-4041Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Organism:yeast· 2 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Organism:fungi (other)· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adrien BirotiD· 2 shared Jean‐Paul JaverzatiD· 2 shared Sabine Vaur· 2 shared Stéphanie Vazquez· 2 shared Adèle L. MarstoniD· 1 shared Ajuna AzadiD· 1 shared Albin SandeliniD· 1 shared Amélie Feytout· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersMolecular Biology

Adrien BirotORCID

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Author profile →

3 papers

Recent·Most cited

Interplay between cohesin and TORC1 links chromosome segregation and gene expression to environmental changes

Dorian Besson, Sabine Vaur, Stéphanie Vazquez, Sylvie Tournier, Yannick Gachet, Adrien Birot, Stéphane Claverol, Adèle L. Marston, Anastasios E. Damdimopoulos, Karl Ekwall, Jean‐Paul Javerzat

This study shows that TORC1 modulates cohesin functions in chromosome segregation and gene expression, linking environmental changes to chromosome stability.

eLife · Jun 1, 2026Peer-reviewedMolecular Biology

The CDK Pef1 and Protein Phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes

Adrien Birot, Marta Tormos-Pérez, Sabine Vaur, Amélie Feytout, Julien Jaegy, Dácil Alonso Gil, Stéphanie Vazquez, Karl Ekwall, Jean‐Paul Javerzat

The paper shows that Pef1 and PP4 regulate cohesin binding in fission yeast by opposing each other's effects on Rad21 phosphorylation.

eLife · Jan 2, 2020Peer-reviewedMolecular Biology

Comprehensive profiling of the fission yeast transcription start site activity during stress and media response

Malte Thodberg, Axel Thieffry, Jette Bornholdt, Mette Boyd, Christian Holmberg, Ajuna Azad, Christopher Thomas Workman, Yun Chen, Karl Ekwall, Olaf Nielsen, Albin Sandelin

This study provides a comprehensive TSS map for fission yeast under various stress and media conditions using CAGE, revealing new insights into gene regulation and promoter diversity.

Nucleic Acids Research · Nov 26, 2018Peer-reviewedGenomics