Adrien Birot

Interplay between cohesin and TORC1 links chromosome segregation and gene expression to environmental changes

This study shows that TORC1 modulates cohesin functions in chromosome segregation and gene expression, linking environmental changes to chromosome stability.

RNA-binding protein Mub1 and the nuclear RNA exosome act to fine-tune environmental stress response

The paper identifies Mub1 as an RNA-binding protein that regulates exosome-dependent mRNA degradation, affecting stress response and gene expression.

The CDK Pef1 and Protein Phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes

The paper shows that Pef1 and PP4 regulate cohesin binding in fission yeast by opposing each other's effects on Rad21 phosphorylation.

Histone deacetylation promotes transcriptional silencing at facultative heterochromatin

The paper shows that HDAC-dependent histone deacetylation is critical for transcriptional silencing of facultative heterochromatin in fission yeast.