Ayumi Hirano‐Iwata

Microfluidic platforms for probing spontaneous functional recovery in hierarchically modular neuronal networks

This study uses microfluidic platforms to investigate how damage to hub or peripheral connections in modular neuronal networks affects recovery, finding that hub damage leads to delayed recovery through alternative pathway formation.

Modeling interregional propagation of α-synuclein in human striatal-midbrain assembloids

This study uses human striatal-midbrain assembloids to show that α-synuclein pathology spreads from the striatum to midbrain dopaminergic neurons, causing functional impairment.

Online supervised learning of temporal patterns in biological neural networks under feedback control

This paper develops a closed-loop biological neural network system that learns and generates temporal patterns through feedback control, demonstrating adaptability and reduced synchronization.

Modular architecture confers robustness to damage and facilitates recovery in spiking neural networks modeling in vitro neurons

This paper models how modular structure and spike-timing-dependent plasticity influence recovery in damaged neuronal networks.