Yoshito Masamizu

Microfluidic platforms for probing spontaneous functional recovery in hierarchically modular neuronal networks

This study uses microfluidic platforms to investigate how damage to hub or peripheral connections in modular neuronal networks affects recovery, finding that hub damage leads to delayed recovery through alternative pathway formation.

Modeling interregional propagation of α-synuclein in human striatal-midbrain assembloids

This study uses human striatal-midbrain assembloids to show that α-synuclein pathology spreads from the striatum to midbrain dopaminergic neurons, causing functional impairment.

ARViS: A bleed-free multi-site automated injection robot for accurate, fast, and dense delivery of virus to mouse and marmoset brains

ARViS enables precise, fast, and dense viral injection in mouse and marmoset brains with minimal bleeding, facilitating biosensor expression for imaging studies.

Dynamics of motor direction representation in the primate premotor and primary motor cortices during sensorimotor learning

This study investigates how motor direction representation changes in primate premotor and primary motor cortices during learning, finding that PMdc neurons dynamically adjust their preferred direction while M1 neurons maintain stability.