Jun B. Takahashi

This paper presents a novel monkey model with impaired DISC1 gene to study adolescent prodromal phenotypes of psychiatric disorders, finding altered social behavior and disrupted brain connectivity.

This study uses human striatal-midbrain assembloids to show that α-synuclein pathology spreads from the striatum to midbrain dopaminergic neurons, causing functional impairment.

This study generates and maintains hindbrain-like neural stem cells without xeno- or basic fibroblast growth factors using three chemicals, showing long-term stability and potential for disease modeling and therapy.

This study shows that the interhemispheric pathway's role in motor recovery changes from inhibitory to facilitatory in primates after corticospinal tract lesioning, affecting hand movements during early recovery.

The paper introduces a platform for label-free electrophysiological live-cell imaging of neuronal networks, demonstrating its capabilities with long-term recordings and analysis tools.