Biological Aging of the Cardiopulmonary System
D K Liu, Pramath Doddaballapur, Zhongyu Cai, Rira Choi, Jack Di Palo, Nicole M. Guerrera, Nebal Abu Hussein, Meredith S. Gwin, Liqin Lin, Siming Zheng, Yuening Zhang, A. Justet, Abhay B. Ramachandra, Xiting Yan, Edward P. Manning
This study quantifies biological cardiopulmonary aging in mice by integrating biomechanics and single-cell transcriptomics, revealing non-linear aging patterns and cell-type-specific gene expression changes.
bioRxiv · Jun 12, 2026 · PreprintPhysiology