Author

Adrian Creanga

National Institutes of HealthORCID 0000-0002-3087-8397Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Masaru KanekiyoiD· 3 shared Andrew J. BorstiD· 2 shared Connor WilliamsiD· 2 shared Douglas S. ReediD· 2 shared Michelle RavichandraniD· 2 shared Neil P. KingiD· 2 shared Rebecca A. GillespieiD· 2 shared Sarah F. AndrewsiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Masaru KanekiyoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

De novo design of protein nanoparticles with integrated functional motifs

Cyrus M. Haas, Sanela Rankovic, Hanul K Lewis, Kenneth D. Carr, Connor Weidle, Sophie S Gerdes, L. Nuss, Felicitas Ruiz, Syed Moiz, Maggie Fiorelli, Emily Grey, Jackson McGowan, N. Pavan Kumar, Adrian Creanga, Alex Kang, , Neil P. King

This paper designs de novo protein nanoparticles with integrated functional motifs, demonstrating their ability to form structured assemblies and elicit immune responses in mice.

bioRxiv · Jan 2, 2026 · PreprintBiochemistry

Functional, Immunogenetic, and Structural Convergence in Influenza Immunity between Humans and Macaques

Maya Sangesland, Ning Li, Yaroslav Tsybovsky, Megan D. Rodgers, Julianna Han, Alesandra J. Rodriguez, James A. Ferguson, Amy R. Henry, Sarah D. Smith, Jesmine Roberts-Torres, Rebecca A. Gillespie, Cuiping Liu, Jonah S. Merriam, Tyler Stephens, Connor Williams, , Masaru Kanekiyo

This study shows that macaques can elicit human-like broadly neutralizing antibodies against influenza HA stem regions, with similar immunogenetic and structural features.

Science Translational Medicine · Sep 10, 2025Peer-reviewedImmunology

Structural Convergence and Water-Mediated Substrate Mimicry Enable Broad Neuraminidase Inhibition by Human Antibodies

Julia Lederhofer, Andrew J. Borst, Lam Nguyen, Rebecca A. Gillespie, Connor Williams, Emma L. Walker, Julie E. Raab, Christina Yap, Daniel Ellis, Adrian Creanga, Hyon‐Xhi Tan, Thi H. T. Do, Michelle Ravichandran, Adrian B. McDermott, Valerie Le Sage, , Masaru Kanekiyo

This study identifies human antibodies that broadly inhibit influenza neuraminidase by mimicking its substrate through structural convergence and water-mediated interactions.

Nature Communications · Aug 1, 2025Peer-reviewedImmunology