Robbee Wedow

The paper shows cellular morphology is a polygenic trait by integrating perturbation data, genetic variation, and cross-modal modeling to predict morphology from gene expression.

This study identifies 52 genetic variants associated with adolescent-onset depression through a large GWAS, revealing age-specific mechanisms and potential drug targets.

The paper identifies genetic loci associated with survey nonresponse behaviors and shows their genetic correlation with education and health.

GWAS in over one million individuals identify 611 loci across risk tolerance and risky behaviors, revealing shared genetic architecture and implicating glutamatergic and GABAergic neurotransmission.

This study conducts a trans-ancestral GWAS of alcohol dependence, identifying genetic variants and correlations with psychiatric disorders.

MTAG improves GWAS results by combining summary statistics across traits, increasing significant loci and enhancing polygenic score variance.