Synthetic BiologybioRxivPreprint
Heterologous engineering of receptors using OrthoRep (HERO) for directed evolution of GPCRs in yeast
Christien Dykstra, Björn D. M. Bean, Olivier Rousseau…·Vincent J. J. Martin
The paper improves GPCR biosensors in yeast using a new platform called HERO, achieving significant sensitivity gains through directed evolution.
DOI 10.64898/2026.09.30.755785