Author
Concordia UniversityORCID 0000-0003-2409-3902Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Christien Dykstra, Björn D. M. Bean, Olivier Rousseau…·Vincent J. J. Martin
The paper improves GPCR biosensors in yeast using a new platform called HERO, achieving significant sensitivity gains through directed evolution.
Björn D. M. Bean, Malcolm S. Whiteway, Vincent J. J. Martin
The paper introduces a CRISPR-Cas9 toolkit for markerless yeast gene localization and overexpression, enabling efficient genomic modifications and subcellular compartment labeling.
Björn D. M. Bean, Colleen J. Mulvihill, Riddhiman K. Garge…·Vincent J. J. Martin
This study engineers yeast to produce cholesterol, enabling functional expression of human opioid and other GPCRs, creating biosensors with measurable agonist responses and antagonist inhibition.
Samantha Katarzyna Dziurdzik, Björn D. M. Bean, Michael Davey, Elizabeth Conibear
The paper identifies a disease-causing mutation in VPS13D that disrupts adaptor binding and membrane recruitment in yeast, supporting a conserved role for the VAB domain.