Author

Eloise J. Lockyer

The Francis Crick InstituteORCID 0000-0002-3180-6387Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1 Organism:virus· 1

Frequent Co-Authors

Francesca TorelliiD· 2 shared Moritz TreeckiD· 2 shared Simon W ButterworthiD· 2 shared Amelia Edwards· 1 shared Ana N. MatiasiD· 1 shared Anita A. KoshyiD· 1 shared Franziska HildebrandtiD· 1 shared Jennifer E. Pearson-FarriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Francesca TorelliORCID

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2 papers

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedApr 16, 2025

In vivo CRISPR screens identify GRA12 as a transcendent secreted virulence factor across Toxoplasma gondii strains and mouse subspecies

Francesca Torelli, Simon Butterworth, Eloise J. Lockyer…·Moritz Treeck

The paper identifies GRA12 as a critical secreted virulence factor in Toxoplasma gondii that functions across different parasite strains and mouse species.

5 citations

mousevirus

𝕏 PostBluesky

Molecular BiologybioRxivPreprintApr 21, 2023

Mapping host-microbe transcriptional interactions by dual perturb-seq

Simon W Butterworth, Kristina Kordova, Sambamurthy Chandrasekaran…·Moritz Treeck

This paper introduces dual perturb-seq, a method combining CRISPR screening and single-cell RNA-sequencing to identify host-microbe transcriptional interactions, revealing new effector proteins in Toxoplasma gondii.

3 citations

humanscRNA-seq

𝕏 PostBluesky