Author

Davide D’Onghia

Università degli Studi del Piemonte Orientale “Amedeo Avogadro”ORCID 0000-0002-3196-940XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander K. Ebralidze· 1 shared Angela Di BaldassarreiD· 1 shared Annalisa Di RuscioiD· 1 shared Barbara GhinassiiD· 1 shared Daniel Geoffrey TeneniD· 1 shared Giorgia MaroniiD· 1 shared Giulia GaggiiD· 1 shared Juan Rodrigo Patiño-MercauiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alexander K. Ebralidze

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1 paper

Recent·Most cited

Small activating RNA AW1-51 (CEBPA-51) elicits targeted DNA demethylation to promote gene activation

Giulia Gaggi, Juan Rodrigo Patiño-Mercau, Marta Borchiellini, Mailin Li, Lucrezia Rinaldi, Giorgia Maroni, Davide D’Onghia, Susumu S. Kobayashi, Mahmoud Adel Bassal, Nagy Adley Habib, Pedro P. Medina, Angela Di Baldassarre, Barbara Ghinassi, Alexander K. Ebralidze, Simone Ummarino, , Annalisa Di Ruscio

This study identifies the mechanism by which AW1-51, a small activating RNA, promotes DNA demethylation and reactivation of the CEBPA gene in cancer.

bioRxiv · Sep 29, 2025 · PreprintMolecular Biology