Catarina Rosa

This study shows that acetyl-CoA synthetase (ACAS) in Plasmodium falciparum is essential for nuclear histone acetylation, which regulates gene expression and the transcriptional cycle during the parasite's life cycle.

The paper uses Micro-C to map DNA-DNA contacts in Plasmodium falciparum, revealing heterochromatic and euchromatic structures mediated by MORC/ApiAP2 and other factors.

The paper investigates the role of cohesin in regulating stage-specific gene expression in Plasmodium falciparum, showing that SMC3 represses genes until their appropriate time of expression.