Author

Edwin García

The Francis Crick InstituteORCID 0000-0002-3263-6260Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:fluorescence / live-cell microscopy· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

P. M. W. FrenchiD· 4 shared Iain A. McNeishiD· 2 shared Sunil KumariD· 2 shared Adam G. McleaniD· 1 shared Alana BurrelliD· 1 shared Aleksandar P. IvanoviD· 1 shared Amy StrangeiD· 1 shared Arturo G. VesgaiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersBioengineering

P. M. W. FrenchORCID

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Author profile →

4 papers

Recent·Most cited

Quantitative evaluation of LED based optical autofocus module

S. Habte, S. Kumar, J. LIGHTLEY, Edwin García, M. A. A. Neil, P. M. W. French

The paper evaluates an LED-based optical autofocus module using 2D autocorrelation analysis and demonstrates its axial stability over time.

Journal of Microscopy · Jul 29, 2026Peer-reviewedBioengineering

Assessing PARP trapping dynamics in ovarian cancer using a CRISPR-engineered FRET biosensor

Daniel Marks, Edwin García, Sunil Kumar, Katie Tyson, Caroline Koch, Aleksandar P. Ivanov, Joshua B. Edel, Hasan Mirza, William Flanagan, Christopher W. Dunsby, P. M. W. French, Iain A. McNeish

This paper develops a CRISPR-engineered FRET biosensor to study PARP trapping dynamics in ovarian cancer cells and identifies reduced trapping in PARPi-resistant models.

Cell Reports Methods · Dec 30, 2025Peer-reviewedCancer Biology

VP-CLEM-Kit: An accessible pipeline for visual proteomics using super resolution volume correlative light and electron microscopy (SR-vCLEM)

Dumisile Lumkwana, Jonathan Lightley, Arturo G. Vesga, Joost de Folter, Marie‐Charlotte Domart, Catherine Maclachlan, Sunil Kumar, James Evans, Christopher J. Peddie, Alana Burrell, Azumi Yoshimura, Asandile Mangali, Nicola Vahrjmeijer, Meenal Bhaga, Catherine Smit, , Lucy Collinson

The paper introduces VP-CLEM-Kit, a cost-effective SR-vCLEM pipeline for visual proteomics, achieving 5-fold resolution improvement at 7-fold lower cost.

bioRxiv · Apr 8, 2025 · PreprintCell Biology

PolSpec: polarisation-based detection for spectral classification of optical signals

Huihui Liu, Sunil Kumar, Edwin García, Darren P. Ennis, Iain A. McNeish, P. M. W. French

PolSpec uses polarisation optics to enable rapid, flexible, and cost-effective hyperspectral imaging with reduced data volume.

Journal of Biophotonics · Mar 24, 2025Peer-reviewedBiophysics