Author

Carol Sheppard

Imperial College LondonORCID 0000-0002-3285-3804Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Assay:metagenomics· 1 Organism:multiple species· 1 Research Focus:phylogenetics / evolution· 1 Assay:protein structure· 1

Frequent Co-Authors

Maryn D. BrowniD· 2 shared William BarclayiD· 2 shared Amalie B. RasmusseniD· 1 shared Amy Mccarron· 1 shared Callum MagilliD· 1 shared Charles J.L. Levitt· 1 shared Claire Mary SmithiD· 1 shared Daniel H. GoldhilliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Maryn D. BrownORCID

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2 papers

Recent·Most cited

MicrobiologyCell chemical biologyPeer-reviewedMar 1, 2026

Influenza A virus polymerase co-opts distinct sets of host proteins for RNA transcription or replication

Amalie B. Rasmussen, Olivia C. Swann, Jonathan C. Brown…·William Barclay

This study identifies host proteins co-opted by influenza A virus polymerase for transcription or replication using differential interactome screening.

4 citationstop 1%

proteomicsexperimental assay

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MicrobiologyNature CommunicationsPeer-reviewedJan 16, 2026

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Polymerase mutations underlie early adaptation of H5N1 influenza virus to dairy cattle and other mammals.

Vidhi Dholakia, Jessica L. Quantrill, Samuel A. S. Richardson…·Daniel H. Goldhill

Cattle B3.13 H5N1 polymerase gained PB2 M631L and PA K497R, boosting replication in bovine and human cells via better bovine ANP32A use; later PB2 E627K and D740N add activity.

47 citationstop 1%

virusmultiple species

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