Author

Vidhi Dholakia

Royal Veterinary CollegeORCID 0009-0002-2820-1499Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Approach:comparative / phylogenetic analysis· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Daniel H. GoldhilliD· 2 shared Fernando CapelasteguiiD· 2 shared Amy Mccarron· 1 shared Callum MagilliD· 1 shared Carol SheppardiD· 1 shared Claire Mary SmithiD· 1 shared Damien C. TullyiD· 1 shared Ecco StalleriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMicrobiology

Daniel H. GoldhillORCID

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2 papers

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedJan 16, 2026

✦ In-depth digest

Polymerase mutations underlie early adaptation of H5N1 influenza virus to dairy cattle and other mammals.

Vidhi Dholakia, Jessica L. Quantrill, Samuel A. S. Richardson…·Daniel H. Goldhill

Cattle B3.13 H5N1 polymerase gained PB2 M631L and PA K497R, boosting replication in bovine and human cells via better bovine ANP32A use; later PB2 E627K and D740N add activity.

47 citationstop 1%

virusmultiple species

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MicrobiologybioRxivPreprintOct 27, 2025

An evolutionary approach to identify mammalian adaptive mutations in the avian influenza polymerase complex

Fernando Capelastegui, Vidhi Dholakia, Damien C. Tully, Daniel H. Goldhill

This study identifies novel mammalian adaptive mutations in avian influenza polymerase complex using phylogenetic analysis and experimental assays.

DOI 10.1101/2025.10.27.684835

humanmouse

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