Systems BiologybioRxivPreprint
A stress-function tradeoff organizes epithelial heterogeneity across spatial scales in the human thyroid
Yael Korem Kohanim, Tal Barkai, Roy Novoselsky…·Ruslan M. Medzhitov
The paper uses spatial transcriptomics to analyze thyroid heterogeneity, identifying a damage-response thyrocyte state that balances with hormone-producing states across scales.
DOI 10.64898/2026.03.12.711294