Author

Roy Novoselsky

Weizmann Institute of ScienceORCID 0000-0002-4464-0179Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:spatial transcriptomics· 4 Approach:statistical model· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:clustering· 2 Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Inna GoliandiD· 4 shared Merav KedmiiD· 4 shared Ofra GolaniiD· 4 shared Shalev ItzkovitziD· 4 shared Tal BarkaiiD· 4 shared Hadas Keren‐ShauliD· 3 shared Keren Bahar HalperniD· 3 shared Sapir ShiriD· 3 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersSystems Biology

Inna GoliandORCID

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4 papers

Recent·Most cited

Subcellular mRNA localization patterns across tissues resolved with spatial transcriptomics

Roy Novoselsky, Ofra Golani, Tal Barkai, Merav Kedmi, Inna Goliand, Michal Fine, Ilan Kent, Ido Nachmany, Shalev Itzkovitz

This study uses spatial transcriptomics to map subcellular mRNA localization across tissues, revealing conserved and tissue-specific patterns.

Nature Communications · Apr 20, 2026Peer-reviewedSystems Biology

A spatial transcriptomics atlas of live donors reveals unique zonation patterns in the healthy human liver

Oran Yakubovsky, Keren Bahar Halpern, Sapir Shir, Roy Novoselsky, Amichay Afriat, Adi Egozi, Tal Barkai, Yotam Harnik, Rouven Hoefflin, Yael Korem Kohanim, Ofra Golani, Inna Goliand, Yoseph Addadi, Merav Kedmi, Hadas Keren‐Shaul, , Shalev Itzkovitz

Spatial transcriptomics of live healthy donor livers shows most hepatocyte genes are zonated, with key functions pericentrally shifted versus mouse, pig, boar and cow.

Nature · Apr 15, 2026Peer-reviewedCell Biology✦ In-depth digest

A stress-function tradeoff organizes epithelial heterogeneity across spatial scales in the human thyroid

Yael Korem Kohanim, Tal Barkai, Roy Novoselsky, Sapir Shir, Keren Bahar Halpern, Shlomit Reich-Zeliger, Jacob Elkahal, Idit Tessler, Shaked Shivatzki, Ignat Schwartz, Eric Remer, Galit Avior, Rouven Hoefflin, Merav Kedmi, Hadas Keren‐Shaul, , Ruslan M. Medzhitov

The paper uses spatial transcriptomics to analyze thyroid heterogeneity, identifying a damage-response thyrocyte state that balances with hormone-producing states across scales.

bioRxiv · Mar 16, 2026 · PreprintSystems Biology

Spatial Rewiring of Enterocyte Identity in Celiac Disease

Tal Barkai, Rachel Frieman-Sharabi, Keren Bahar Halpern, Roy Novoselsky, Yael Korem Kohanim, Sapir Shir, Ofra Golani, Inna Goliand, Yoseph Addadi, Merav Kedmi, Hadas Keren‐Shaul, Lena Prichislov, Anat Guz‐Mark, Hadassah Nissim, R Shamir, , Shalev Itzkovitz

This study uses spatial and single-cell transcriptomics to show that celiac disease alters enterocyte states by promoting aberrant zonal co-expression and metaplastic cells.

bioRxiv · Feb 17, 2026 · PreprintSystems Biology