Zhijian Zhao

The paper introduces a large-scale dataset of functional responses from mouse ganglion cells, enabling population-level analyses and computational modeling of retinal computation.

This study investigates how PARP regulates calpain activity in rd1 mouse photoreceptors and identifies potential therapeutic targets for inherited retinal degenerations.

This study identifies Esr1 activation as a protective mechanism against neuroinflammation in retinal degeneration, showing it suppresses Tnf-α signaling and reduces photoreceptor death.

This study investigates how nitric oxide modulates contrast suppression in specific mouse retinal ganglion cell types using two-photon imaging and MEA recordings.

This paper introduces a technique combining two-photon microscopy and multi-electrode array recordings to study the functional interaction between photoreceptors and retinal ganglion cells in acute retinal explants.

This paper describes a hemispheric dome setup for naturalistic visual stimulation in head-fixed mice, showing that eye position shifts in response to visual input.

This paper establishes a STED microscopy protocol for super-resolution imaging of whole-mount mouse retinas, achieving sub-120 nm resolution for subcellular structures.

The paper uses a UV-green camera to study mouse visual environments and finds that natural scene statistics shape color discrimination and retinal processing in the upper visual field.

The paper develops a method to image the entire inner plexiform layer of the retina at once, revealing response speed gradients in bipolar cells and isolating experimental batch effects.

This paper introduces a flexible spatial visual stimulator with arbitrary spectrum control for use in vision research, demonstrating its application in mouse and zebrafish models.

The paper develops a Bayesian statistical pipeline for analyzing two-photon imaging data using Gaussian Process Regression to infer neural activity and guide experimental design.