Inherited retinal degenerations: PARP regulates calpain activation via TRPM2 channels in rd1 mouse photoreceptors
Jie Yan, Lei Kong, Zhijian Zhao, Qianlu Yang, Lan Wang, Qianxi Yang, Christian Harteneck, Kangwei Jiao, Zhulin Hu, François Paquet‐Durand
This study investigates how PARP regulates calpain activity in rd1 mouse photoreceptors and identifies potential therapeutic targets for inherited retinal degenerations.
bioRxiv · Nov 13, 2025 · PreprintNeuroscience