Author

M. Ariel Spurrier

Duke UniversityORCID 0000-0002-3314-9683Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1 Organism:rat· 1 Organism:virus· 1

Frequent Co-Authors

Barton F. HaynesiD· 2 shared Nicholas S. HeatoniD· 2 shared Aaron G. SchmidtiD· 1 shared Aaron May· 1 shared Albert Guzman· 1 shared Alexis Johnson· 1 shared Alon Herschchorn· 1 shared Amit SharmaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersImmunology

Barton F. HaynesORCID

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2 papers

Recent·Most cited

Elicitation of stem-directed antibodies in rhesus macaques by a conventional hemagglutinin immunogen

Shuqin Gu, Joel Finney, Kan Luo, Sarah M. Valencia, Dieter Mielke, Tarra A. Von Holle, DJ Marshall, Robert Parks, Laura L. Sutherland, Richard M. Scearce, Kevin J. Wiehe, Sampa Santra, Summer Harris, Jacquelyn DuVall, Chelsea D. Landon, , Michael Anthony Moody

This study shows that a conventional H1 HA trimer vaccine elicits stem-directed antibodies in rhesus macaques that provide broad protection against H1N1 and H5N1 influenza.

bioRxiv · Jul 21, 2026 · PreprintImmunology

An integrated workflow for structural virology with a 100 keV electron microscope

Rasangi Pathirage, Moumita Dutta, Ruth Parsons, Muralikrishna Lella, Emma Atwood, Qianyi E. Zhang, Aaron May, Alexis Johnson, Xiao Huang, Jordan Flemming, Ujjwal Kumar, Bahjat F. Marayati, M. Ariel Spurrier, Coco Liu, Junlin Zhuo, , Priyamvada Acharya

This paper describes a user-managed 100 keV electron microscope setup for structural virology, enabling high-quality cryo-EM data collection and analysis within a laboratory setting.

bioRxiv · Dec 10, 2025 · PreprintBiochemistry