Author

Laren Riesche

University of PennsylvaniaORCID 0000-0002-3327-4089Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Eric A. Rhon‐CalderóniD· 3 shared Marisa S. BartolomeiiD· 3 shared Richard M. SchultziD· 3 shared Alexandra J. Savage· 2 shared Cassidy N. HemphilliD· 2 shared Ana Domingo-MuelasiD· 1 shared Benjamin Aaron GarciaiD· 1 shared Christopher J. KrappiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersDevelopmental Biology

Eric A. Rhon‐CalderónORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In Vitro Fertilization Accelerates Female Reproductive Aging Through Early Ovarian Failure

Eric A. Rhon‐Calderón, Cassidy N. Hemphill, Alexandra J. Savage, Ana Domingo-Muelas, Zhengfeng Liu, Christopher J. Krapp, Laren Riesche, Nicolas Plachta, Richard M. Schultz, Marisa S. Bartolomei

This study shows that in vitro fertilization (IVF) accelerates reproductive aging in female mice by causing premature ovarian failure, with altered ovarian function and epigenetic changes.

bioRxiv · Oct 13, 2025 · PreprintDevelopmental Biology

In Vitro Fertilization induces reproductive changes in male mouse offspring and has multigenerational effects

Eric A. Rhon‐Calderón, Cassidy N. Hemphill, Alexandra J. Savage, Laren Riesche, Richard M. Schultz, Marisa S. Bartolomei

This study shows that IVF in mice leads to reproductive and molecular changes in male offspring, which are transmitted across generations.

JCI Insight · Mar 4, 2025Peer-reviewedDevelopmental Biology

Sex-specific effects of in vitro fertilization on adult metabolic phenotypes and hepatic transcriptomic and proteomic pathways in mouse.

Laren Narapareddy, Eric A. Rhon‐Calderón, Lisa A. Vrooman, Josue Baeza, Duy K. Nguyen, Yemin Lan, Benjamin Aaron Garcia, Richard M. Schultz, Marisa S. Bartolomei

This study examines sex-specific metabolic and transcriptomic effects of IVF in mice, finding sex-dimorphic dysregulation of SREBP pathways and placental DNA methylation changes linked to cholesterol levels.

bioRxiv · Sep 23, 2020 · PreprintDevelopmental Biology