Author

Lauren B. Ostermann

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-3330-2174Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Abhishek MaitiiD· 1 shared Andrea D. BedoyiD· 1 shared Bing Z. CarteriD· 1 shared Darah A Scruggs· 1 shared Dong CheniD· 1 shared Edward AyoubiD· 1 shared Eiji SugiharaiD· 1 shared Hideaki Mizuno· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Abhishek MaitiORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Dual MYC and GSPT1 Protein Degrader for MYC-Driven Cancers

Yuki Nishida, Valeria Impedovo, Edward Ayoub, Natalia Baran, Darah A Scruggs, Hideaki Mizuno, Shayaun Khazaei, Lauren B. Ostermann, Sandeep Singh, Andrea D. Bedoy, Po Yee Mak, Bing Z. Carter, Eiji Sugihara, Tetsuya Takimoto, Youzhi Tong, , Michael Andreeff

This paper identifies a novel MYC-GSPT1 feedback loop and reports a dual degrader, GT19630, that effectively targets MYC-driven cancers with anti-proliferative and apoptotic effects.

bioRxiv · Apr 24, 2025 · PreprintCancer Biology