Author

Siwang Yu

Peking UniversityORCID 0000-0002-3336-202XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Bingwei WangiD· 1 shared Daotong LiiD· 1 shared J M LiuiD· 1 shared Jianyuan LuoiD· 1 shared Ke Wang· 1 shared Lihua Qin· 1 shared Lu QiuiD· 1 shared Meng WangiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPhysiology

Bingwei WangORCID

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2 papers

Recent·Most cited

Identification of leptolin as a novel anti-obesity adipokine

J M Liu, Bingwei Wang, Zhijie Su, Xiaoxv Han, Miao He, Yun Zhao, Yujia Hou, Daotong Li, Weiguang Zhang, Lihua Qin, Ke Wang, Yanchun Li, Yi Yan, Siwang Yu, Xiaoshuai Huang, , Ruimao Zheng

This study identifies leptolin as a novel adipokine that improves metabolic status by promoting fat mobilization and energy expenditure, and shows its potential as a therapeutic agent for obesity.

Advanced Science · May 25, 2026Peer-reviewedPhysiology

Oncogenic activation of Nrf2 by specific knockout of Nrf1α that acts as a dominant tumor repressor

Lu Qiu, Meng Wang, Shaofan Hu, Xufang Ru, Yonggang Ren, Zhengwen Zhang, Siwang Yu, Yiguo Zhang

This study shows that Nrf1 knockout leads to Nrf2 hyperactivation, promoting hepatoma, and reveals a feedback loop between Nrf1 and Nrf2 in tumor suppression.

Cancers · Dec 17, 2018Peer-reviewedMolecular Biology