Author

Jonathan Jung

University of Massachusetts Chan Medical SchoolORCID 0000-0002-3342-1245Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Dorothy P. SchaferiD· 2 shared Brian PopkoiD· 1 shared Cathleen M. LutziD· 1 shared Cory M. WillisiD· 1 shared Daniel S. ReichiD· 1 shared Daryl A. BoscoiD· 1 shared Debra Cameron· 1 shared Del Hayden GaddiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Dorothy P. SchaferORCID

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2 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedMar 20, 2024

Expression of ALS-PFN1 impairs vesicular degradation in iPSC-derived microglia

Salome Funes, Jonathan Jung, Del Hayden Gadd…·Daryl A. Bosco

This study shows that ALS-linked PFN1 mutations impair vesicular degradation in iPSC-derived microglia by disrupting autophagy, which can be mitigated by Rapamycin.

24 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeuroscienceImmunityPeer-reviewedDec 26, 2019

Targeted complement inhibition at synapses prevents microglial synaptic engulfment and synapse loss in demyelinating disease

Sebastian Werneburg, Jonathan Jung, Rejani B. Kunjamma…·Dorothy P. Schafer

This study identifies synapse loss and microglial synaptic engulfment in MS models and demonstrates that targeted complement inhibition prevents synapse loss and visual dysfunction.

440 citationstop 1%

humanmouse

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